M. lignano Single Cells Juveniles
Mlig455
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MligTC455_15137 (CG5522)

Mlig455 TC Mlig455 genes Homologs Pfam Full annotation
MligTC455_15137 Mlig455_067270 CG5522; RALGPS1; Ralgps2 RasGEF domain Mlig455_067270:
{TRANSSPLICED}
{Pfam: RasGEF domain [PF00617.21, score=146.0]}
{Human: ENSG00000136828, RALGPS1, Ral GEF with PH domain and SH3 binding motif 1, [Score=249, Expect=6e-75]; ENSG00000116191, RALGPS2, Ral GEF with PH domain and SH3 binding motif 2, [Score=249, Expect=6e-73]}
{Mouse: ENSMUSG00000026594, Ralgps2, Ral GEF with PH domain and SH3 binding motif 2, [Score=249, Expect=1e-72]; ENSMUSG00000038831, Ralgps1, Ral GEF with PH domain and SH3 binding motif 1, [Score=244, Expect=3e-71]}
{Dmel: FBgn0034158, CG5522, [Score=241, Expect=8e-69]}
{Celegans: WBGene00017891, rgl-1, Ral GDS-Like, [Score=70.9, Expect=2e-12]}
{Smed: dd_Smed_v6_9244_0_1, dd_Smed_v6_9244_0_1, [Score=212, Expect=2e-57]}

Links: Tomoseq.

Expression, Z-scaled

Variance, Z-scaled

Clusters

Expression, raw

Similar genes by expression

Nr. Mlig455 TC Pearson corr. Mlig455 genes Homologs Pfam Full annotation
1. MligTC455_05081 0.555 Mlig455_004977 Details
2. MligTC455_01874 0.555 Mlig455_006664 Details
3. MligTC455_13790 0.555 Mlig455_016071 C2 domain Details
4. MligTC455_16970 0.555 Mlig455_018064 FLOT1; Flo1; Flot1 SPFH domain / Band 7 family Details
5. MligTC455_31728 0.555 Mlig455_018806 Details
6. MligTC455_22482 0.555 Mlig455_019819 Details
7. MligTC455_24507 0.555 Mlig455_023223
Mlig455_023224		 Details
8. MligTC455_13076 0.555 Mlig455_024842 Details
9. MligTC455_29528 0.555 Mlig455_025666 SLC43A3 Major Facilitator Superfamily Details
10. MligTC455_49644 0.555 Mlig455_027199 Reverse transcriptase (RNA-dependent DNA polymerase) Details
11. MligTC455_06651 0.555 Mlig455_028194 CG13229 Serpentine type 7TM GPCR chemoreceptor Srw Details
12. MligTC455_52392 0.555 Mlig455_028273 CG13625 Details
13. MligTC455_57346 0.555 Mlig455_037381 Details
14. MligTC455_12579 0.555 Mlig455_039084 LRCH3; Lrch; Lrch3 Leucine rich repeat Details
15. MligTC455_34535 0.555 Mlig455_049248 CG30273; Gm5767 LITAF-like zinc ribbon domain Details
16. MligTC455_53315 0.555 Mlig455_052524 Domain of unknown function (DUF1846) Details
17. MligTC455_28163 0.555 Mlig455_055128 Reverse transcriptase (RNA-dependent DNA polymerase) Details
18. MligTC455_21939 0.555 Mlig455_058008 Details
19. MligTC455_08457 0.555 Mlig455_064003 CHRNA3; Chrna3; nAChRalpha7 Neurotransmitter-gated ion-channel ligand binding domain Details
20. MligTC455_08458 0.555 Mlig455_064042 CHRNA3; Chrna3; nAChRalpha7 Neurotransmitter-gated ion-channel ligand binding domain Details
21. MligTC455_48415 0.508 Mlig455_035974 Details
22. MligTC455_57390 0.487 Mlig455_040521 Details
23. MligTC455_15136 0.472 Mlig455_000802 CG5522; RALGPS2; Ralgps2 RasGEF domain Details
24. MligTC455_15165 0.467 Mlig455_022783
Mlig455_022968		 Details
25. MligTC455_04951 0.467 Mlig455_024295 Tro Details
26. MligTC455_11548 0.467 Mlig455_038900 CD209; lectin-33A Lectin C-type domain Details
27. MligTC455_15890 0.467 Mlig455_059636 CD209; lectin-33A Lectin C-type domain Details
28. MligTC455_11549 0.467 Mlig455_063869 CD209; lectin-33A Lectin C-type domain Details
29. MligTC455_49764 0.461 Mlig455_004382 TTC39A; Ttc39a Protein of unknown function (DUF3808) Details
30. MligTC455_49765 0.461 Mlig455_037196 TTC39A; Ttc39a Protein of unknown function (DUF3808) Details
31. MligTC455_38882 0.446 Mlig455_070467 Glycosyltransferase family 92 Details
32. MligTC455_10943 0.433 Mlig455_066927 Details
33. MligTC455_30442 0.426 Mlig455_002167
Mlig455_002267
Mlig455_002311
Mlig455_007989
Mlig455_031987
Mlig455_036803		 CASP8; Casp9; Drice Caspase domain Details
34. MligTC455_34005 0.422 Mlig455_065861 Details
35. MligTC455_28448 0.409 Mlig455_034262
Mlig455_067299		 HYDIN Family of unknown function (DUF6195) Details
36. MligTC455_32362 0.407 Mlig455_009286 Details
37. MligTC455_48637 0.407 Mlig455_049996 ANKRD17; Ankrd6; mask Ankyrin repeats (3 copies) Details
38. MligTC455_19136 0.404 Mlig455_044611 LARS2; Lars2; LeuRS-m tRNA synthetases class I (I, L, M and V) Details
39. MligTC455_44835 0.399 Mlig455_046218 Details
40. MligTC455_49526 0.399 Mlig455_050949 CALM2; Calm1; Cam EF-hand domain pair Details
41. MligTC455_51328 0.392 Mlig455_005958 Details
42. MligTC455_11275 0.389 Mlig455_000949 Tetraspanin family Details
43. MligTC455_56942 0.389 Mlig455_002670 Details
44. MligTC455_03607 0.389 Mlig455_003471 Protein of unknown function (DUF445) Details
45. MligTC455_48149 0.389 Mlig455_005539 Details
46. MligTC455_06496 0.389 Mlig455_006214 Details
47. MligTC455_19646 0.389 Mlig455_014818 Details
48. MligTC455_11060 0.389 Mlig455_026391 Details
49. MligTC455_00067 0.389 Mlig455_035302 Details
50. MligTC455_15803 0.389 Mlig455_039323 RGS12; Rgs12; loco Regulator of G protein signaling domain Details
51. MligTC455_29577 0.389 Mlig455_034332
Mlig455_043861		 Details
52. MligTC455_52666 0.389 Mlig455_044631 Details
53. MligTC455_33182 0.389 Mlig455_051889 Details
54. MligTC455_04688 0.389 Mlig455_059947 Akap5 Details
55. MligTC455_34367 0.389 Mlig455_012646
Mlig455_028858
Mlig455_064019		 Reverse transcriptase (RNA-dependent DNA polymerase) Details
56. MligTC455_07943 0.389 Mlig455_064043 Details
57. MligTC455_48150 0.389 Mlig455_064143 Details
58. MligTC455_08563 0.389 Mlig455_032294
Mlig455_068472		 HPGD; Hpgd; Pdh short chain dehydrogenase Details
59. MligTC455_07653 0.381 Mlig455_005690 Details
60. MligTC455_50035 0.379 Mlig455_000039 SPHK1; Sk1; Sphk1 Diacylglycerol kinase catalytic domain Details
61. MligTC455_20061 0.379 Mlig455_063029 AMT; Amt; CG6415 Aminomethyltransferase folate-binding domain Details
62. MligTC455_28106 0.376 Mlig455_037446
Mlig455_041053		 Details
63. MligTC455_26206 0.373 Mlig455_028076
Mlig455_028138
Mlig455_028270		 Tetraspanin family Details
64. MligTC455_45402 0.371 Mlig455_001374 DAT; SLC6A2; Slc6a2 Sodium:neurotransmitter symporter family Details
65. MligTC455_28621 0.371 Mlig455_027409 SEMA5B; Sema5b; Sema5c Sema domain Details
66. MligTC455_20254 0.368 Mlig455_029558 Details
67. MligTC455_40738 0.368 Mlig455_031939 CALM2; Calm3; Cam EF hand Details
68. MligTC455_17525 0.366 Mlig455_059098 Amiloride-sensitive sodium channel Details
69. MligTC455_50036 0.366 Mlig455_063714 SPHK1; Sk1; Sphk1 Diacylglycerol kinase catalytic domain Details
70. MligTC455_42184 0.365 Mlig455_003395 Phosphoinositide 3-kinase C2 Details
71. MligTC455_41907 0.363 Mlig455_020658 CADPS; Cadps MUN domain Details
72. MligTC455_24508 0.363 Mlig455_006045
Mlig455_006046
Mlig455_023285
Mlig455_023286
Mlig455_056744		 Details
73. MligTC455_40737 0.362 Mlig455_031853 CALM2; Calm3; Cam EF hand Details
74. MligTC455_33845 0.361 Mlig455_004238 Details
75. MligTC455_26303 0.359 Mlig455_041962 alphaSnap Soluble NSF attachment protein, SNAP Details
76. MligTC455_34003 0.357 Mlig455_042218
Mlig455_065856		 Details
77. MligTC455_34004 0.357 Mlig455_065875 Details
78. MligTC455_18716 0.356 Mlig455_013385 PLSCR1; Plscr2; scramb2 Scramblase Details (TF)
79. MligTC455_44180 0.356 Mlig455_037643 TRIM3; Trim3 Ring finger domain Details
80. MligTC455_07654 0.355 Mlig455_005644
Mlig455_008675		 DNAAF4; Dyx1c1; Stip1 Tetratricopeptide repeat Details
81. MligTC455_15363 0.355 Mlig455_041174 Diap2; XIAP; Xiap Inhibitor of Apoptosis domain Details
82. MligTC455_18413 0.353 Mlig455_044730 Details
83. MligTC455_50034 0.35 Mlig455_000005 SPHK1; Sk1; Sphk2 Diacylglycerol kinase catalytic domain Details
84. MligTC455_02786 0.35 Mlig455_065118 PRR9 Cysteine rich repeat Details
85. MligTC455_45680 0.345 Mlig455_064286 CG14906; METTL4; Mettl4 MT-A70 Details
86. MligTC455_43693 0.345 Mlig455_024778
Mlig455_066105
Mlig455_068668		 Details
87. MligTC455_44181 0.345 Mlig455_069912 TRIM3; Trim3 Ring finger domain Details
88. MligTC455_07434 0.338 Mlig455_000460 Details
89. MligTC455_01545 0.338 Mlig455_000869 Details
90. MligTC455_01247 0.338 Mlig455_000914 Details
91. MligTC455_27478 0.338 Mlig455_000927 LRP2; Lrp2; mgl Low-density lipoprotein receptor domain class A Details
92. MligTC455_38904 0.338 Mlig455_001538 Domain of unknown function (DUF5746) Details
93. MligTC455_09469 0.338 Mlig455_001885 Pancreatic hormone peptide Details
94. MligTC455_54545 0.338 Mlig455_004057 Details
95. MligTC455_06554 0.338 Mlig455_004297 Glycine rich protein Details
96. MligTC455_27976 0.338 Mlig455_005942 GRM2; Grm2; mtt Receptor family ligand binding region Details
97. MligTC455_21164 0.338 Mlig455_006622 Details
98. MligTC455_46600 0.338 Mlig455_007943 Details
99. MligTC455_23768 0.338 Mlig455_008100 Details
100. MligTC455_00961 0.338 Mlig455_010098 Reverse transcriptase (RNA-dependent DNA polymerase) Details
101. MligTC455_56285 0.338 Mlig455_010600 Details
102. MligTC455_01002 0.338 Mlig455_010713 Details
103. MligTC455_47608 0.338 Mlig455_011112 NaCP60E; SCN11A; Scn10a Ion transport protein Details
104. MligTC455_06093 0.338 Mlig455_011579 Details
105. MligTC455_09602 0.338 Mlig455_012026 CG43729; STAC2; Stac2 SH3 domain Details
106. MligTC455_03606 0.338 Mlig455_013713 DDE superfamily endonuclease Details
107. MligTC455_14943 0.338 Mlig455_014051 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 Details
108. MligTC455_52766 0.338 Mlig455_014174 Details
109. MligTC455_32432 0.338 Mlig455_014378 Details
110. MligTC455_13537 0.338 Mlig455_014382 Details
111. MligTC455_28328 0.338 Mlig455_005321
Mlig455_015449		 Adenovirus endoprotease Details
112. MligTC455_03267 0.338 Mlig455_018292 Cysteine rich repeat Details
113. MligTC455_45390 0.338 Mlig455_020094 Details
114. MligTC455_24470 0.338 Mlig455_020119 Pancreatic hormone peptide Details
115. MligTC455_43736 0.338 Mlig455_021692 CREB1; Creb1; CrebB bZIP transcription factor Details (TF)
116. MligTC455_25548 0.338 Mlig455_022208 SDK2; Sdk2; sdk Fibronectin type III domain Details
117. MligTC455_38701 0.338 Mlig455_015653
Mlig455_023761		 ANK1; Ank1; CG3104; CG42672; FPGT-TNNI3K; Tnni3k Ankyrin repeats (3 copies) Details
118. MligTC455_29784 0.338 Mlig455_024256 Integrase zinc binding domain Details
119. MligTC455_01009 0.338 Mlig455_024589 Details
120. MligTC455_35862 0.338 Mlig455_025750 Interferon-related protein conserved region Details
121. MligTC455_37205 0.338 Mlig455_026085 Details
122. MligTC455_08992 0.338 Mlig455_027248 Details
123. MligTC455_17331 0.338 Mlig455_027864 Details
124. MligTC455_13510 0.338 Mlig455_028877 Details
125. MligTC455_12547 0.338 Mlig455_029109 Details
126. MligTC455_06159 0.338 Mlig455_030303 Details
127. MligTC455_54945 0.338 Mlig455_030586 Protein of unknown function (DUF3760) Details
128. MligTC455_22745 0.338 Mlig455_032577 PKM; Pkm; PyK Pyruvate kinase, barrel domain Details
129. MligTC455_22746 0.338 Mlig455_032638 PKM; Pkm; PyK Pyruvate kinase, barrel domain Details
130. MligTC455_28837 0.338 Mlig455_034210 Hrd3; SEL1L2; Sel1l2 Sel1 repeat Details
131. MligTC455_41511 0.338 Mlig455_034958 Glut1; SLC2A3; Slc2a5 Sugar (and other) transporter Details
132. MligTC455_40484 0.338 Mlig455_035093 Details
133. MligTC455_03335 0.338 Mlig455_038009 Cornifin (SPRR) family Details
134. MligTC455_29780 0.338 Mlig455_039027 MAP3K4; Map3k4; Mekk1 Protein kinase domain Details
135. MligTC455_18186 0.338 Mlig455_039173 Details
136. MligTC455_32521 0.338 Mlig455_040932 Details
137. MligTC455_32522 0.338 Mlig455_040944 Details
138. MligTC455_31121 0.338 Mlig455_019142
Mlig455_041109		 SETMAR Transposase (partial DDE domain) Details
139. MligTC455_13994 0.338 Mlig455_041638 Gimap9 AIG1 family Details
140. MligTC455_26308 0.338 Mlig455_042032 Soluble NSF attachment protein, SNAP Details
141. MligTC455_31779 0.338 Mlig455_043209 TRIM3; Trim3; tn NHL repeat Details
142. MligTC455_43907 0.338 Mlig455_044346 Details
143. MligTC455_31325 0.338 Mlig455_026709
Mlig455_044580
Mlig455_050736
Mlig455_050745		 Reverse transcriptase (RNA-dependent DNA polymerase) Details
144. MligTC455_40159 0.338 Mlig455_045827
Mlig455_045843		 Reverse transcriptase (RNA-dependent DNA polymerase) Details
145. MligTC455_55188 0.338 Mlig455_045926 Details
146. MligTC455_15974 0.338 Mlig455_046153
Mlig455_046238		 Pancreatic hormone peptide Details
147. MligTC455_38906 0.338 Mlig455_001535
Mlig455_046567		 Domain of unknown function (DUF5746) Details
148. MligTC455_31917 0.338 Mlig455_047059 Mekk1; WNK4; Wnk4 Protein kinase domain Details
149. MligTC455_31797 0.338 Mlig455_047809 Details
150. MligTC455_01430 0.338 Mlig455_047886 Details
151. MligTC455_41908 0.338 Mlig455_048858 CADPS; Cadps MUN domain Details
152. MligTC455_30898 0.338 Mlig455_049826 Hip14; ZDHHC17; Zdhhc17 DHHC palmitoyltransferase Details
153. MligTC455_37944 0.338 Mlig455_050320 Details
154. MligTC455_10842 0.338 Mlig455_041244
Mlig455_053093		 HGTX; NKX6-3; Nkx6-3 Homeodomain Details (TF)
155. MligTC455_13705 0.338 Mlig455_053299 Details
156. MligTC455_36197 0.338 Mlig455_053513 TNS1; Tns1; by Phosphotyrosine-binding domain Details
157. MligTC455_38574 0.338 Mlig455_022071
Mlig455_053611		 CAPN11; CalpA; Capn9 Calpain family cysteine protease Details
158. MligTC455_12194 0.338 Mlig455_054298 Details
159. MligTC455_09351 0.338 Mlig455_054530 Details
160. MligTC455_32288 0.338 Mlig455_000769
Mlig455_055328		 Details
161. MligTC455_41395 0.338 Mlig455_056185 CDC14A; Cdc14a; cdc14 Dual specificity protein phosphatase, N-terminal half Details
162. MligTC455_01052 0.338 Mlig455_057202 Details
163. MligTC455_57250 0.338 Mlig455_057707 Details
164. MligTC455_08179 0.338 Mlig455_058894 Details
165. MligTC455_22853 0.338 Mlig455_019405
Mlig455_059068		 Integrase zinc binding domain Details
166. MligTC455_42852 0.338 Mlig455_059938 CG30339; TTPAL; Ttpal CRAL/TRIO domain Details
167. MligTC455_57251 0.338 Mlig455_059970 Details
168. MligTC455_28321 0.338 Mlig455_060693 DNA polymerase type B, organellar and viral Details
169. MligTC455_36198 0.338 Mlig455_061010 TNS1; Tns1; by Phosphotyrosine-binding domain Details
170. MligTC455_18392 0.338 Mlig455_061371 EMC8; EMC8-9; Emc8 Uncharacterised protein family (UPF0172) Details
171. MligTC455_43785 0.338 Mlig455_061392 MgtE intracellular N domain Details
172. MligTC455_18187 0.338 Mlig455_051641
Mlig455_062006		 Details
173. MligTC455_29102 0.338 Mlig455_062696 RNase H-like domain found in reverse transcriptase Details
174. MligTC455_04342 0.338 Mlig455_063655 Cartilage oligomeric matrix protein Details
175. MligTC455_27081 0.338 Mlig455_064122 Reverse transcriptase (RNA-dependent DNA polymerase) Details
176. MligTC455_09530 0.338 Mlig455_064478 Details
177. MligTC455_16542 0.338 Mlig455_064717 Details
178. MligTC455_47415 0.338 Mlig455_065682 Details
179. MligTC455_16178 0.338 Mlig455_066102 Details
180. MligTC455_20659 0.338 Mlig455_066591 Details
181. MligTC455_19384 0.338 Mlig455_068372 Details
182. MligTC455_22392 0.338 Mlig455_068489 Details
183. MligTC455_01933 0.338 Mlig455_069256 Details
184. MligTC455_10294 0.338 Mlig455_069762 Details
185. MligTC455_06448 0.338 Mlig455_022314
Mlig455_069882		 Pancreatic hormone peptide Details
186. MligTC455_09835 0.338 Mlig455_069983 Details
187. MligTC455_42644 0.334 Mlig455_004159 Details
188. MligTC455_48636 0.333 Mlig455_011518
Mlig455_011596		 ANK2; Ankrd6; mask Ankyrin repeats (3 copies) Details
189. MligTC455_20256 0.332 Mlig455_040468 Details
190. MligTC455_28103 0.327 Mlig455_009044 Details
191. MligTC455_49804 0.326 Mlig455_007934
Mlig455_008037		 CG8611; DDX31; Ddx31 DEAD/DEAH box helicase Details
192. MligTC455_11839 0.325 Mlig455_024549 Details
193. MligTC455_32363 0.325 Mlig455_037021 Details
194. MligTC455_31291 0.325 Mlig455_013887
Mlig455_057722		 CG11155; GRIA2; Gria4 Ligated ion channel L-glutamate- and glycine-binding site Details
195. MligTC455_27001 0.324 Mlig455_015615 NAV2; Nav2; sick Details
196. MligTC455_31421 0.324 Mlig455_031337 CG4670; QSOX2; Qsox2 Erv1 / Alr family Details
197. MligTC455_15362 0.324 Mlig455_041011
Mlig455_041120		 Diap2; XIAP; Xiap Inhibitor of Apoptosis domain Details
198. MligTC455_20255 0.322 Mlig455_040441 Details
199. MligTC455_29205 0.322 Mlig455_052289 ANK1; Ank; Ankrd50 Ankyrin repeats (3 copies) Details
200. MligTC455_34143 0.321 Mlig455_002688 PDZ domain Details
201. MligTC455_42326 0.32 Mlig455_056343 EVX1; Evx1; eve Homeodomain Details (TF)
202. MligTC455_21560 0.32 Mlig455_059034 AIG1 family Details
203. MligTC455_50371 0.318 Mlig455_014288 Details
204. MligTC455_34002 0.318 Mlig455_042149 Details
205. MligTC455_29906 0.317 Mlig455_023040
Mlig455_069770		 MAP3K4; Map3k4; Mekk1 Protein kinase domain Details
206. MligTC455_27365 0.316 Mlig455_008275 Details
207. MligTC455_26718 0.315 Mlig455_002028 CHRNA7; Chrna7; nAChRalpha5 Neurotransmitter-gated ion-channel ligand binding domain Details
208. MligTC455_09137 0.315 Mlig455_016284 Details
209. MligTC455_24510 0.315 Mlig455_018570 Details
210. MligTC455_45109 0.315 Mlig455_032630 MAPK7; Mapk12; p38a Protein kinase domain Details
211. MligTC455_10718 0.315 Mlig455_040222 Details
212. MligTC455_02765 0.315 Mlig455_046340 Domain of unknown function (DUF4573) Details
213. MligTC455_45401 0.314 Mlig455_001360 Zinc finger, C3HC4 type (RING finger) Details
214. MligTC455_29903 0.314 Mlig455_040864 MAP3K4; Map3k4; Mekk1 Protein kinase domain Details
215. MligTC455_48028 0.312 Mlig455_007274 SPSB4; Spsb1; gus Details
216. MligTC455_28341 0.312 Mlig455_014141 Details
217. MligTC455_31193 0.312 Mlig455_055801 Details
218. MligTC455_52023 0.312 Mlig455_032206
Mlig455_060756		 UNG; Ung Uracil DNA glycosylase superfamily Details
219. MligTC455_25479 0.309 Mlig455_002918 Btk; Btk29A; ITK Protein tyrosine and serine/threonine kinase Details
220. MligTC455_29884 0.309 Mlig455_060830 Details
221. MligTC455_33846 0.309 Mlig455_061676 DHX58; Dcr-2; Dhx58 RNA dependent RNA polymerase Details
222. MligTC455_37874 0.308 Mlig455_012392 Dl; NOTCH2; Notch2 Calcium-binding EGF domain Details
223. MligTC455_42325 0.308 Mlig455_016673 EVX1; Evx1; eve Homeodomain Details (TF)
224. MligTC455_24541 0.308 Mlig455_022288 HHAT; Hhat MBOAT, membrane-bound O-acyltransferase family Details
225. MligTC455_49640 0.308 Mlig455_063691 Details
226. MligTC455_12580 0.305 Mlig455_042777 LRCH3; Lrch; Lrch3 Leucine rich repeat Details
227. MligTC455_21561 0.305 Mlig455_059037 Details
228. MligTC455_35442 0.304 Mlig455_037038 CG32645; Oacyl Acyltransferase family Details
229. MligTC455_10069 0.303 Mlig455_044048 Details
230. MligTC455_40451 0.302 Mlig455_000638 Details
231. MligTC455_49805 0.301 Mlig455_008078 CG8611; DDX31; Ddx31 DEAD/DEAH box helicase Details
232. MligTC455_29261 0.3 Mlig455_024258 Details
233. MligTC455_53470 0.3 Mlig455_025677 Details

Similar genes by variation

Nr. Mlig455 TC Pearson corr. Mlig455 genes Homologs Pfam Full annotation
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