M. lignano Single Cells Juveniles
Mlig455
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MligTC455_48176 (MRPL11)

Mlig455 TC Mlig455 genes Homologs Pfam Full annotation
MligTC455_48176 Mlig455_033843 MRPL11; Mrpl11; mRpL11 Ribosomal protein L11, N-terminal domain Mlig455_033843:
{TRANSSPLICED}
{Pfam: Ribosomal protein L11, N-terminal domain [PF03946.16, score=83.8]; Ribosomal protein L11, RNA binding domain [PF00298.21, score=82.6]}
{Human: ENSG00000174547, MRPL11, mitochondrial ribosomal protein L11, [RH, Score=159, Expect=6e-49]}
{Mouse: ENSMUSG00000024902, Mrpl11, mitochondrial ribosomal protein L11, [RH, Score=154, Expect=2e-47]}
{Dmel: FBgn0038234, mRpL11, mitochondrial ribosomal protein L11, [RH, Score=190, Expect=1e-61]}
{Celegans: WBGene00015133, mrpl-11, Probable 39S ribosomal protein L11, mitochondrial, [RH, Score=165, Expect=9e-52]}
{Smed: dd_Smed_v6_4881_0_1, dd_Smed_v6_4881_0_1, [RH, Score=156, Expect=1e-48]}

Links: Tomoseq.

Expression, Z-scaled

Variance, Z-scaled

Clusters

Expression, raw

Similar genes by expression

Nr. Mlig455 TC Pearson corr. Mlig455 genes Homologs Pfam Full annotation
1. MligTC455_43581 0.458 Mlig455_042725
Mlig455_042827
Mlig455_063146		 CG11155; CG3822; GRIA2; Gria2 Ligand-gated ion channel;
Receptor family ligand binding region		 Details
2. MligTC455_55802 0.453 Mlig455_015511 Aromatic acid exporter family member 2 Details
3. MligTC455_51635 0.453 Mlig455_042974 CG2006; DTWD1; Dtwd1 DTW domain Details
4. MligTC455_51636 0.453 Mlig455_065291
Mlig455_065315		 CG2006; DTWD1; Dtwd1 DTW domain Details
5. MligTC455_43614 0.41 Mlig455_059631
Mlig455_059645		 Details
6. MligTC455_18875 0.405 Mlig455_017470 SLC18B1; Slc18b1 Major Facilitator Superfamily Details
7. MligTC455_39980 0.399 Mlig455_019252
Mlig455_035527		 Dhap-at; GNPAT; Gnpat Glycerol-3-phosphate acyltransferase C-terminal region Details
8. MligTC455_32463 0.396 Mlig455_066538 BLVRB; Blvrb NAD(P)H-binding Details
9. MligTC455_46829 0.39 Mlig455_033589
Mlig455_062873		 Details
10. MligTC455_46000 0.388 Mlig455_000630 Details
11. MligTC455_01791 0.388 Mlig455_005666 Cell division protein ZapB Details
12. MligTC455_09037 0.388 Mlig455_013219
Mlig455_013245
Mlig455_013314		 Amiloride-sensitive sodium channel Details
13. MligTC455_46970 0.388 Mlig455_023542
Mlig455_023648		 Details
14. MligTC455_48069 0.388 Mlig455_045278 CG31548; HSD11B1; Hsd11b1 short chain dehydrogenase Details
15. MligTC455_11230 0.388 Mlig455_046902 ShK domain-like Details
16. MligTC455_02951 0.388 Mlig455_055300 PRR9 Details
17. MligTC455_19722 0.379 Mlig455_000253 Helix-loop-helix DNA-binding domain Details
18. MligTC455_21238 0.379 Mlig455_005974 Details
19. MligTC455_19723 0.379 Mlig455_058537 Helix-loop-helix DNA-binding domain Details
20. MligTC455_14698 0.378 Mlig455_016423
Mlig455_018959		 Endonuclease-reverse transcriptase Details
21. MligTC455_15373 0.377 Mlig455_005138 EXOSC4; Exosc4; Ski6 3' exoribonuclease family, domain 1 Details
22. MligTC455_15553 0.375 Mlig455_031390 CG32344; DDX54; Ddx54 DEAD/DEAH box helicase Details
23. MligTC455_35329 0.371 Mlig455_032927
Mlig455_032941
Mlig455_032974		 CG14618; TRMT10B; TRMT10C; Trmt10a; Trmt10c tRNA (Guanine-1)-methyltransferase Details
24. MligTC455_36652 0.366 Mlig455_054146 CG14231; OSGEPL1; Osgepl1 tRNA N6-adenosine threonylcarbamoyltransferase Details
25. MligTC455_28465 0.366 Mlig455_056640 Details
26. MligTC455_11904 0.366 Mlig455_052381
Mlig455_064133		 Details
27. MligTC455_51891 0.365 Mlig455_037545
Mlig455_059603
Mlig455_070949		 NVL; Nvl; smid ATPase family associated with various cellular activities (AAA) Details
28. MligTC455_40549 0.363 Mlig455_034121 BIRC5; Birc5; Det Inhibitor of Apoptosis domain Details
29. MligTC455_27005 0.361 Mlig455_033683 KLHDC8A; Klhdc8b Kelch motif Details
30. MligTC455_36741 0.356 Mlig455_058926 CG8036; TKT; Tkt Transketolase, thiamine diphosphate binding domain Details
31. MligTC455_21263 0.349 Mlig455_034631 Details
32. MligTC455_23900 0.349 Mlig455_046112 Details
33. MligTC455_16295 0.349 Mlig455_057293
Mlig455_059607		 AIF; AIFM1; Aifm1 Pyridine nucleotide-disulphide oxidoreductase Details
34. MligTC455_18876 0.347 Mlig455_030924 SLC18B1; Slc18b1 Major Facilitator Superfamily Details
35. MligTC455_25419 0.344 Mlig455_021972 CRNKL1; Crnkl1; crn HAT (Half-A-TPR) repeat Details
36. MligTC455_34605 0.344 Mlig455_038363 DDX4; Ddx4; vas DEAD/DEAH box helicase Details
37. MligTC455_36653 0.342 Mlig455_052146
Mlig455_060684		 CG14231; OSGEPL1; Osgepl1 tRNA N6-adenosine threonylcarbamoyltransferase Details
38. MligTC455_48436 0.341 Mlig455_022258 TRAF3; Traf2; Traf4 Details
39. MligTC455_24729 0.341 Mlig455_066060 Aminotransferase class-V Details
40. MligTC455_41685 0.34 Mlig455_047202 MSH4; Msh4 MutS domain III Details
41. MligTC455_44705 0.34 Mlig455_048425 Details
42. MligTC455_44656 0.34 Mlig455_003770
Mlig455_003782
Mlig455_054342		 THYN1; Thyn1 EVE domain Details (TF)
43. MligTC455_44433 0.337 Mlig455_020702
Mlig455_020770		 GATC; GatC; Gatc Glu-tRNAGln amidotransferase C subunit Details
44. MligTC455_48322 0.337 Mlig455_035101
Mlig455_053307
Mlig455_062411		 CG16935; ZADH2; Zadh2 Zinc-binding dehydrogenase Details
45. MligTC455_24721 0.336 Mlig455_007749 Details
46. MligTC455_31817 0.335 Mlig455_040709
Mlig455_064581		 BC017158; C16orf58; CG10338 Vitamin B6 photo-protection and homoeostasis Details
47. MligTC455_47815 0.334 Mlig455_041890 Gm9833; MYEF2; rump RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Details
48. MligTC455_51776 0.334 Mlig455_060815 CEP120; Cep120 Details
49. MligTC455_33867 0.333 Mlig455_005075 MED13; Med13; skd Mediator complex subunit 13 C-terminal domain Details
50. MligTC455_44692 0.332 Mlig455_026776 SUPT16H; Supt16; dre4 FACT complex subunit (SPT16/CDC68) Details
51. MligTC455_31621 0.332 Mlig455_027745 ush Zinc finger, C2H2 type Details
52. MligTC455_41078 0.332 Mlig455_031144
Mlig455_031152		 CDC20; Calx; Cdc20; SLC8A3; Slc8a3; fzy Calx-beta domain;
WD domain, G-beta repeat		 Details
53. MligTC455_39619 0.33 Mlig455_006330 CG12288; RBM34; Rbm34 NRDE-2, necessary for RNA interference Details
54. MligTC455_21262 0.329 Mlig455_001277
Mlig455_031445		 Details
55. MligTC455_47813 0.328 Mlig455_032907 Gm9833; MYEF2; rump RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Details
56. MligTC455_12713 0.325 Mlig455_012819 ERR; ESRRB; Esrrb Zinc finger, C4 type (two domains) Details (TF)
57. MligTC455_29342 0.325 Mlig455_025176
Mlig455_025188		 Details
58. MligTC455_37648 0.325 Mlig455_042650
Mlig455_042684		 DCAF1; Dcaf1; mahj Details
59. MligTC455_42486 0.325 Mlig455_056354 Details
60. MligTC455_33506 0.325 Mlig455_057522 RPS19; RpS19a; Rps19 Ribosomal protein S19e Details
61. MligTC455_46935 0.324 Mlig455_011475 Ribosome biogenesis protein Nop16 Details
62. MligTC455_51777 0.324 Mlig455_060853 CEP120; Cep120 Details
63. MligTC455_21505 0.324 Mlig455_004243
Mlig455_063139		 Replication protein A OB domain Details
64. MligTC455_33944 0.323 Mlig455_023999 Details
65. MligTC455_44693 0.323 Mlig455_051787 SUPT16H; Supt16; dre4 FACT complex subunit (SPT16/CDC68) Details
66. MligTC455_19440 0.323 Mlig455_060962 HASPIN; Haspin Haspin like kinase domain Details
67. MligTC455_20199 0.322 Mlig455_021885 KCNMA1; Kcnma1; slo Calcium-activated BK potassium channel alpha subunit Details
68. MligTC455_30743 0.322 Mlig455_060907
Mlig455_069368		 AGO3; PIWIL1; Piwil1 Piwi domain Details
69. MligTC455_41686 0.321 Mlig455_048475 MSH4; Msh4; Msh6 MutS domain V Details
70. MligTC455_07242 0.32 Mlig455_001381 Details
71. MligTC455_07745 0.32 Mlig455_003887 Details
72. MligTC455_40685 0.32 Mlig455_004153 BTB/POZ domain Details
73. MligTC455_36015 0.32 Mlig455_004222 GIIIspla2; PLA2G3; Pla2g3 Phospholipase A2 Details
74. MligTC455_10690 0.32 Mlig455_004223 Rdx family Details
75. MligTC455_38733 0.32 Mlig455_004261 BCKDHB; Bckdhb; CG17691 Transketolase, pyrimidine binding domain Details
76. MligTC455_38734 0.32 Mlig455_004310 BCKDHB; Bckdhb; CG17691 Transketolase, pyrimidine binding domain Details
77. MligTC455_38735 0.32 Mlig455_004329 ASPDH; Aspdh Domain of unknown function DUF108 Details
78. MligTC455_57569 0.32 Mlig455_004867 Ribosomal protein S31e Details
79. MligTC455_53121 0.32 Mlig455_005453 ISXO2-like transposase domain Details
80. MligTC455_21249 0.32 Mlig455_007283 Ndae1; SLC4A4; Slc4a8 HCO3- transporter family Details
81. MligTC455_11718 0.32 Mlig455_009100 Details
82. MligTC455_06285 0.32 Mlig455_009345 Details
83. MligTC455_23590 0.32 Mlig455_012666 PLK4; Plk4; SAK Protein kinase domain Details
84. MligTC455_24646 0.32 Mlig455_013889 Putative transmembrane family 234 Details
85. MligTC455_46547 0.32 Mlig455_013892 Details
86. MligTC455_14369 0.32 Mlig455_015561 CG9467; KCTD21; Kctd7 BTB/POZ domain Details
87. MligTC455_37203 0.32 Mlig455_016211 TRAF2; Traf2 TRAF-type zinc finger Details
88. MligTC455_25383 0.32 Mlig455_017641 SF3B3; Sf3b3 CPSF A subunit region Details
89. MligTC455_21946 0.32 Mlig455_018218 CDH18; CadN; Cdh18 Cadherin cytoplasmic region Details
90. MligTC455_36072 0.32 Mlig455_019055 Details
91. MligTC455_32388 0.32 Mlig455_020365 Details
92. MligTC455_29462 0.32 Mlig455_021960 RPL5; RpL5; Rpl5 Ribosomal large subunit proteins 60S L5, and 50S L18 Details
93. MligTC455_01538 0.32 Mlig455_022098 Details
94. MligTC455_15113 0.32 Mlig455_022691 EGF-like domain Details
95. MligTC455_54788 0.32 Mlig455_022992 Details
96. MligTC455_54787 0.32 Mlig455_023084 Details
97. MligTC455_51084 0.32 Mlig455_023014
Mlig455_023114		 PDLIM7; Pdlim7; Zasp52 LIM domain Details
98. MligTC455_12295 0.32 Mlig455_024929
Mlig455_024963		 Details
99. MligTC455_40721 0.32 Mlig455_028262 CHAF1A; Caf1-180; Chaf1a Chromatin assembly factor 1 subunit A Details
100. MligTC455_16394 0.32 Mlig455_031639 Details
101. MligTC455_15823 0.32 Mlig455_031852
Mlig455_031938		 CCNB1; Ccnb2; CycB Cyclin, N-terminal domain Details
102. MligTC455_00410 0.32 Mlig455_032596 Details
103. MligTC455_02312 0.32 Mlig455_006094
Mlig455_032878		 Details
104. MligTC455_22851 0.32 Mlig455_032044
Mlig455_033467		 RNase H-like domain found in reverse transcriptase Details
105. MligTC455_05307 0.32 Mlig455_033612 SOX2; Sox2; Sox21a HMG (high mobility group) box Details (TF)
106. MligTC455_04810 0.32 Mlig455_034345
Mlig455_034399		 GABRB3; GLRA4; Gabrb3; Lcch3; ort Neurotransmitter-gated ion-channel ligand binding domain Details
107. MligTC455_04250 0.32 Mlig455_034744 CBX3; Cbx3; HP1b Chromo (CHRromatin Organisation MOdifier) domain Details
108. MligTC455_11644 0.32 Mlig455_034785 Details
109. MligTC455_34647 0.32 Mlig455_009217
Mlig455_037092		 Details
110. MligTC455_09911 0.32 Mlig455_037478 Details
111. MligTC455_45275 0.32 Mlig455_037525 HYD1 signature containing ADP-ribosyltransferase Details
112. MligTC455_12743 0.32 Mlig455_039861 CG2926; PHRF1; Phrf1 Details
113. MligTC455_24583 0.32 Mlig455_023933
Mlig455_040681		 KCTD1; Kctd1 Phage integrase family Details
114. MligTC455_45276 0.32 Mlig455_037563
Mlig455_040852		 HYD1 signature containing ADP-ribosyltransferase Details
115. MligTC455_12583 0.32 Mlig455_042400 Glycosyltransferase sugar-binding region containing DXD motif Details
116. MligTC455_51021 0.32 Mlig455_042594
Mlig455_042637		 7tm Chemosensory receptor Details
117. MligTC455_42155 0.32 Mlig455_026607
Mlig455_042802		 Details
118. MligTC455_55478 0.32 Mlig455_043260 Ribosomal protein S31e Details
119. MligTC455_51879 0.32 Mlig455_044001 Details
120. MligTC455_01234 0.32 Mlig455_045608 Details
121. MligTC455_45724 0.32 Mlig455_046940 DYNC1H1; Dhc64C; Dync1h1 Hydrolytic ATP binding site of dynein motor region Details
122. MligTC455_10638 0.32 Mlig455_047387 PRR9 Details
123. MligTC455_16082 0.32 Mlig455_047900 Family of unknown function (DUF5810) Details
124. MligTC455_24897 0.32 Mlig455_048310
Mlig455_048334
Mlig455_048354		 CG5549; SLC6A5; Slc6a5 Sodium:neurotransmitter symporter family Details
125. MligTC455_16429 0.32 Mlig455_048808 Details
126. MligTC455_14505 0.32 Mlig455_049200 HEY2; Hey; Hey2 Helix-loop-helix DNA-binding domain Details (TF)
127. MligTC455_53364 0.32 Mlig455_051569 Zinc finger, C2H2 type Details
128. MligTC455_19852 0.32 Mlig455_052325 Details
129. MligTC455_53816 0.32 Mlig455_052564 WSC domain Details
130. MligTC455_08498 0.32 Mlig455_053380 Details
131. MligTC455_53817 0.32 Mlig455_053580 WSC domain Details
132. MligTC455_01539 0.32 Mlig455_053636 Details
133. MligTC455_12082 0.32 Mlig455_053835 Details
134. MligTC455_37204 0.32 Mlig455_054272 TRAF-type zinc finger Details
135. MligTC455_48129 0.32 Mlig455_055849 Details
136. MligTC455_28463 0.32 Mlig455_056008 PODNL1; Slit1; Toll-6 Leucine rich repeat Details
137. MligTC455_28464 0.32 Mlig455_056104 SLIT3; Slit2; Toll-6 Leucine rich repeat Details
138. MligTC455_41257 0.32 Mlig455_056117 Details
139. MligTC455_11719 0.32 Mlig455_058097 Details
140. MligTC455_38818 0.32 Mlig455_060036 MMP21; Mmp1; Mmp21 Matrixin Details
141. MligTC455_13490 0.32 Mlig455_060452 Tudor domain Details
142. MligTC455_08939 0.32 Mlig455_062872 Details
143. MligTC455_40350 0.32 Mlig455_063073 ARHGAP19-SLIT1; Arhgap19; RhoGAP54D RhoGAP domain Details
144. MligTC455_08928 0.32 Mlig455_063271 OVOL1; Ovol1; ovo Zinc-finger double domain Details (TF)
145. MligTC455_39872 0.32 Mlig455_019072
Mlig455_064295
Mlig455_064332		 Details
146. MligTC455_24447 0.32 Mlig455_068139 Details
147. MligTC455_12369 0.32 Mlig455_070054 Family of unknown function (DUF5641) Details
148. MligTC455_02524 0.32 Mlig455_070455 Rnp4F Details
149. MligTC455_15114 0.32 Mlig455_022690
Mlig455_022704
Mlig455_070618		 Muc68E; Zan EGF-like domain Details
150. MligTC455_42638 0.319 Mlig455_046644
Mlig455_046665		 Details
151. MligTC455_27262 0.317 Mlig455_051702 KMT2E; Kmt2e; upSET SET domain Details
152. MligTC455_19601 0.317 Mlig455_064158 TMEM128; Tmem128 Details
153. MligTC455_32868 0.316 Mlig455_025290 Details
154. MligTC455_21886 0.315 Mlig455_009535 NUMB; Numb; numb Phosphotyrosine interaction domain (PTB/PID) Details
155. MligTC455_16891 0.315 Mlig455_029698 Details
156. MligTC455_42451 0.315 Mlig455_041813 MRAS; Mras; Ras64B Ras family Details
157. MligTC455_28827 0.315 Mlig455_044793 PTPRD; Ptp99A; Ptprd Protein-tyrosine phosphatase Details
158. MligTC455_20512 0.314 Mlig455_008861 RPA1; RpA-70; Rpa1 Replication factor-A C terminal domain Details
159. MligTC455_31296 0.314 Mlig455_011781 Details
160. MligTC455_33866 0.313 Mlig455_005035 MED13; Med13; skd Mediator complex subunit 13 C-terminal domain Details
161. MligTC455_44231 0.313 Mlig455_020250 CG5245; ZNF724; Zfp72 Zinc-finger double domain Details (TF)
162. MligTC455_29461 0.313 Mlig455_021877 RPL5; RpL5; Rpl5 Ribosomal large subunit proteins 60S L5, and 50S L18 Details
163. MligTC455_28428 0.313 Mlig455_054840 NDC80; Ndc80 HEC/Ndc80p family Details
164. MligTC455_43357 0.312 Mlig455_002141
Mlig455_002241		 PSMD8; Psmd8; Rpn12 CSN8/PSMD8/EIF3K family Details
165. MligTC455_42407 0.312 Mlig455_004618 OST-HTH/LOTUS domain Details
166. MligTC455_15374 0.312 Mlig455_005171 DUSP15; Dusp15; Mkp3 Dual specificity phosphatase, catalytic domain Details
167. MligTC455_47501 0.312 Mlig455_056951 CHD1L; Chd1l; Iswi SNF2-related domain Details
168. MligTC455_41079 0.311 Mlig455_031153 CDC20; Cdc20; fzy WD domain, G-beta repeat Details
169. MligTC455_34779 0.311 Mlig455_045356 La; SSB; Ssb RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Details
170. MligTC455_16936 0.311 Mlig455_049166
Mlig455_049218		 2210016F16Rik; C9orf64; CG9752 Potential Queuosine, Q, salvage protein family Details
171. MligTC455_36654 0.311 Mlig455_054150 Stathmin family Details
172. MligTC455_51610 0.31 Mlig455_023608 CG8525; DERA; Dera DeoC/LacD family aldolase Details
173. MligTC455_53150 0.31 Mlig455_036588 Details
174. MligTC455_36436 0.309 Mlig455_002863 CG9272; NTHL1; Nthl1 HhH-GPD superfamily base excision DNA repair protein Details
175. MligTC455_51436 0.309 Mlig455_044065 CG6923; RNF165; Rnf165 Ring finger domain Details
176. MligTC455_25440 0.309 Mlig455_061218 CG12325; PWP2; Pwp2 WD domain, G-beta repeat Details
177. MligTC455_33504 0.308 Mlig455_021195 XAB2; Xab2; fand Ribosomal protein S19e Details
178. MligTC455_49463 0.308 Mlig455_039577
Mlig455_039592
Mlig455_051387		 CYC1; Cyc1; Cyt-c1 Cytochrome C1 family Details
179. MligTC455_42896 0.308 Mlig455_068325 Details
180. MligTC455_22847 0.307 Mlig455_029515 RPS10; RpS10b; Rps10 Plectin/S10 domain Details
181. MligTC455_40087 0.307 Mlig455_022164
Mlig455_055774		 Seven in absentia protein family Details
182. MligTC455_24842 0.306 Mlig455_014634 TRPM1; Trpm; Trpm1 Ankyrin repeats (3 copies) Details
183. MligTC455_27290 0.306 Mlig455_030127
Mlig455_030193		 CG10365; CHAC2; Chac2 ChaC-like protein Details
184. MligTC455_41432 0.306 Mlig455_059289
Mlig455_065206		 LSM3; LSm3; Lsm3 LSM domain Details
185. MligTC455_05177 0.306 Mlig455_068027 PRR9 Details
186. MligTC455_52776 0.305 Mlig455_014951
Mlig455_045141
Mlig455_045176		 FUT6; FucTA; Fut7 Glycosyltransferase family 10 (fucosyltransferase) C-term Details
187. MligTC455_18207 0.305 Mlig455_049340
Mlig455_049418		 CG10011; GAMT; Gamt Ankyrin repeats (3 copies) Details
188. MligTC455_32686 0.305 Mlig455_057550 BMS1; Bms1; CG7728 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Details
189. MligTC455_42410 0.304 Mlig455_004722 OST-HTH/LOTUS domain Details
190. MligTC455_39959 0.304 Mlig455_012245
Mlig455_012258		 RPL34; RpL34a; Rpl34 Ribosomal protein L34e Details
191. MligTC455_39687 0.304 Mlig455_021114 ATP5F1C; ATPsyngamma; Atp5c1 ATP synthase Details
192. MligTC455_50639 0.304 Mlig455_027350 SSRP1; Ssrp; Ssrp1 POB3-like N-terminal PH domain Details
193. MligTC455_33885 0.304 Mlig455_041304 GNL2; Gnl2; Ns2 NGP1NT (NUC091) domain Details
194. MligTC455_44246 0.304 Mlig455_054454 ARHGAP19; Arhgap19; RhoGAP54D RhoGAP domain Details
195. MligTC455_29463 0.303 Mlig455_021882 RPL5; RpL5; Rpl5 Ribosomal large subunit proteins 60S L5, and 50S L18 Details
196. MligTC455_21048 0.303 Mlig455_022276 EIF3B; Eif3b; eIF3b Eukaryotic translation initiation factor eIF2A Details
197. MligTC455_40884 0.303 Mlig455_051978 Nefh; ZNF512B Details (TF)
198. MligTC455_42894 0.302 Mlig455_007293 CAPRIN1; Capr; Caprin1 Caprin-1 dimerization domain Details

Similar genes by variation

Nr. Mlig455 TC Pearson corr. Mlig455 genes Homologs Pfam Full annotation
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